Distinct human small intestinal microbiome communities underlie visceral hypersensitivity in a humanized mouse model

作者：Işın Y. Comba, Tijs Louwies, Ruben A. Mars, Yang Xiao, Prabhjot Kaur Sekhon, Brian S. Edwards, Adam Willits, Robin Shields‐Cutler, Shreya S. Bellampalli, Arnaldo Mercado‐Perez, Dennis R. Tienter, Lisa Till, David R. Linden, Gianrico Farrugia, Arthur Beyder, Kristen Smith, Purna Kashyap · 发表于：Journal of Clinical Investigation · 年份：2025 · DOI：10.1172/jci190638 · 被引用次数：2 · 研究领域：Gut microbiota and health

Specific small-intestinal bacteria, particularly Enterobacteriaceae, can trigger abdominal pain by activating gut sensory and nerve cells, revealing how microbiota contribute to gastrointestinal symptoms.