Adjacent Rare-Earth Separation via a Protein Atomic Ruler

作者：Xining Qian, Yunxiang Du, Chao Ma, Huijing Cui, Huaxia Zhu, Tongjia Shi, Yang Bai, Fangkun Wang, Zhengqing Li, Jing Yu, Huajian Gao, Hongjie Zhang, Lei Liu, Kai Liu · 发表于：ChemRxiv · 年份：2025 · DOI：10.26434/chemrxiv-2025-p0w0k-v2 · 被引用次数：1 · 研究领域：Radioactive element chemistry and processing、Extraction and Separation Processes、Advanced Materials Characterization Techniques

The separation of rare-earth elements (REEs) poses a formidable challenge due to their nearly identical ionic radii and chemical properties. Here, we present a transformative strategy for REE separation using a multimetal ion-stacking metalloprotein framework (MIF) that functions as an atomic ruler, effectively amplifying subtle differences in REE ionic radii. This approach achieves exceptional selectivity, enabling the separation of all 13 adjacent REE pairs with ultrahigh purity (up to 99.999%). Remarkably, the MIF retains its lanthanide-binding capacity over 410 consecutive absorption-desorption cycles, demonstrating outstanding stability. Structural insights reveal that the MIF’s densely packed REE coordination environment magnifies minute radius variations—a key mechanism underlying its unparalleled separation efficiency. Our MIF-based strategy offers a sustainable, scalable solution to rare-earth separation in industrial applications.