A model based on high-resolution magnetic resonance vessel wall imaging for predicting stroke recurrence in patients with symptomatic intracranial atherosclerosis

作者：Jing Zhao, Xihai Zhao, Zhi-Gang Peng, Jun‐Yan Liu · 发表于：Quantitative Imaging in Medicine and Surgery · 年份：2025 · DOI：10.21037/qims-2025-1201 · 被引用次数：2 · 研究领域：Cerebrovascular and Carotid Artery Diseases、Acute Ischemic Stroke Management、Neurological Disease Mechanisms and Treatments

Background: Due to its high sensitivity and specificity, high-resolution magnetic resonance vessel wall imaging (HRMR-VWI) and other adjunct tools with conventional angiography have been widely applied in the diagnosis of ischemic cerebrovascular disease. The purpose of this study was to construct a model based on HRMR-VWI indicators for predicting ischemic stroke recurrence in patients with symptomatic intracranial atherosclerosis (sICAS). Methods: The data in this study were partly from patients with cerebral infarction or transient ischemic attack attending 18 hospitals (from January 2017 to December 2019) in the ICASMAP study (A Study on the Etiology of Intracranial Artery Stenosis and Atherosclerotic Plaque Prediction Based on High Resolution MRI Technology). The remaining data were from patients with cerebral infarction or transient ischemic attack who were hospitalized in the Hebei Medical University Third Hospital (from January 2020 to December 2023). A total of 540 patients with sICAS were enrolled, all of whom were ≥18 years old, had large arterial atherosclerotic lesions (30-99% stenotic lesions in at least one intracranial artery as confirmed by HRMR-VWI examination, with the stenotic lesions being responsible for the stroke), and experienced ischemic stroke within 2 weeks. The follow-up endpoint event was the recurrence of stroke. Follow-up was completed in 493 of the patients (493/540, 91.30%), the average follow-up time was 43 months, and 65 patients experience...