Analysis of the correlation between PM2.5 and PM10 concentrations and the epidemiology of severe Mycoplasma pneumoniae in the PICU

作者：Yufan Yang, Hengyun He, Wang Chen, Xinping Zhang, Jiaotian Huang, Xiulan Lu, Zhenghui Xiao · 发表于：Scientific Reports · 年份：2025 · DOI：10.1038/s41598-025-20565-x · 被引用次数：3 · 研究领域：Inhalation and Respiratory Drug Delivery、Air Quality and Health Impacts、Pneumonia and Respiratory Infections

This study aimed to analyze the epidemiological characteristics of severe Mycoplasma pneumoniae in the pediatric intensive care unit (PICU) of Hunan Children’s Hospital from 2020 to 2023. This study investigated the epidemiological patterns related to different years, seasons, ages, and sexes, as well as the correlations of PM 2.5 , PM 10 , and NO 2 concentrations, temperature, and humidity with severe Mycoplasma pneumoniae . The goal is to increase awareness of the prevention and control of severe Mycoplasma pneumoniae in the Changsha region, thereby improving clinical outcomes, reducing mortality rates among patients with severe cases, and providing evidence-based guidance for clinical practice. A retrospective analysis was conducted on children diagnosed with severe Mycoplasma pneumoniae in the PICU of Hunan Children’s Hospital from January 2020 to December 2023. The study compared the positivity rates of Mycoplasma infections across different years, seasons, age groups, and sexes. The correlations between PM 2.5 (µg/m 3 ), PM 10 (µg/m 3 ), NO 2 (µg/m 3 ), average temperature (°C), and average relative humidity (%) and the number of cases of severe Mycoplasma pneumoniae were also analyzed. Among 2,047 children with severe pneumonia, the overall MP-IgM positivity rate was 9.5%. Annual positivity rates increased from 6.3% in 2020 to 15.7% in 2023. Rates were highest in summer (15.8%), and preschool children (3–7 years) showed the greatest positivity (30.0%). At pollutant con...