Global, regional, and national burden of asthma from 1990 to 2021: analysis of data from global disease burden in 2021

作者：Cong Hu, Shuxiong Nong, Yixin Chen, Anthony Lin Zhang, Yongfeng Chen, Chenang Liu, Ping Li, Chilin Liao, Meng Wu · 发表于：BMC Pulmonary Medicine · 年份：2025 · DOI：10.1186/s12890-025-03816-5 · 被引用次数：6 · 研究领域：Asthma and respiratory diseases、Delphi Technique in Research、Health Promotion and Cardiovascular Prevention

BACKGROUND: Asthma is one of the diseases that pose a serious threat to human health globally. The Global Burden of Disease (GBD) study from 1990 to 2021 conducted a comprehensive assessment of the prevalence, incidence, mortality, and Disability-Adjusted Life Years (DALY) of asthma. This study particularly focuses on the integration of prevalence data with other indicators and carries out stratified analyses at the global, regional, and national levels based on gender, age, and Socio-Demographic Index (SDI). METHODS: The data for this study is drawn from the 2021 Global Burden of Disease (GBD) study, which provides comprehensive data on diseases, injuries, and risk factors. This study aims to explore the temporal trends of asthma and assess the dynamics of age-standardized prevalence rates (ASPR), incidence rates (ASIR), death rates (ASDR), and disability-adjusted life years (DALYs) for asthma, with the goal achieved by estimating the annual percentage change (EAPC) over the study period. The study conducted a detailed stratification based on gender, 20 age groups, 21 GBD regions, 204 countries and territories, and 5 SDI quintiles. RESULTS: In 2021, asthma continued to impose a substantial burden on the global health landscape, with a total of 260479186.9 (227209547.5-297967236.9) cases and an ASPR of 3340.1 (2905.2-3832.2 per 100,000 people. The ASIR was 37864175.4 (31381241-46919993.7), translating to 516.7 (425.4-646.1) per 100,000 people. In 2021, the number of disabilit...