Figure S2 from Genetic Control of tRNA-Derived Fragments Contributes to Cancer Risk

作者：Bin Li, Hanting Li, Yan Li, Zhirui Chen, Danyi Zou, Chunyi He, Songqiang Li, Kexin Hu, Caibo Ning, Yanmin Li, Hui Geng, Shuhui Yang, Chaoqun Huang, Xiaojun Yang, Qiuhong Wang, Xu Zhu, Xiangpan Li, Ying Zhu, Meng Jin, Xiaoping Miao, Jianbo Tian · 年份：2025 · DOI：10.1158/0008-5472.30363181 · 研究领域：RNA modifications and cancer、RNA and protein synthesis mechanisms

<p>Figure S2. Illustrative examples of immune infiltration and drug response association analyses. A, The number (left y axis) and proportion of tRFs (right y axis) correlated with T cell CD4+ memory resting (top) and T cell gamma delta (bottom) were estimated using the CIBERSORT algorithm. B, Significant tRF-drug response pairs identified in CRC. The top 20 drugs (x axis) significantly associated with tRFs (y axis) are shown in the plot. C, The correlation between tRF-25-0P58309NDJ expression and drug response data of Linsitinib in TCGA CRC tissues. P-values and correlation coefficients were calculated using Spearman’s correlation analyses.</p>