Adoption of polyvinyl alcohol electrospinning materials for skin wound dressing

作者：Shuang Deng, Xing Huang, Zhanrong Kang, Dafeng Xu, Wenbo Luo, Dejian Li · 发表于：Journal of Materials Science Materials in Medicine · 年份：2025 · DOI：10.1007/s10856-025-06945-9 · 被引用次数：9 · 研究领域：Electrospun Nanofibers in Biomedical Applications、Wound Healing and Treatments、Silk-based biomaterials and applications

The effective treatment and repair of skin trauma has always been an important topic of medical research. As an advanced preparation method of nanofibers (NFs), electrospinning (ES) technology shows broad application prospects in the field of skin wound dressing. This review aims to systematically summarize and analyze the process and application research progress of PVA ES materials in skin wound dressing, and explore its mechanism and clinical application prospects in the process of wound healing. By consulting and analyzing the literature about PVA ES materials in recent years, the preparation process, structural properties, and application examples in skin wound dressing were focused on, and the latest experimental research and clinical data were combined to make a comprehensive review. The results suggested that PVA ES material had unique advantages in wound healing. NFs dressings with specific structure and properties can be prepared by adjusting ES parameters. PVA ES dressing not only has excellent physical barrier function, but also can regulate humidity, promote cell proliferation and angiogenesis, thus accelerating wound healing. In addition, the functionally modified PVA fiber dressing also suggested visible effects in antibacterial, anti-inflammatory, and other aspects. Visible progress has been made in the application of PVA ES materials in skin wound dressings. However, further optimization of its preparation process, improvement of functional properties, and la...