Intensive care unit outcomes and prognostic factors of colorectal cancer

作者：Qian Dong, Rui Xia, Xue-zhong Xing, Changsong Wang, Gang Ma, Hongzhi Wang, Biao Zhu, Jianghong Zhao, Dongmin Zhou, Li Zhang, Mingguang Huang, Rongxi Quan, Yong Ye, Guo‐Xing Zhang, Zhengying Jiang, Bing Huang, S. Xu, Yun Xiao, Lin-Lin Zhang, Rui-Yun Lin, Shuli Ma, Yuan Qiu, Zheng Zhen, Ni Sun, Lewu Xian, Ji Li, Ming Zhang, Zhijun Guo, Yong Tao, Xin Zhou, Wei Chen, D F Wang, Ji-Yan Chi, Donghao Wang, Kai-Zhong Liu · 发表于：World Journal of Gastrointestinal Oncology · 年份：2025 · DOI：10.4251/wjgo.v17.i10.108539 · 被引用次数：4 · 研究领域：Sepsis Diagnosis and Treatment、Cardiac, Anesthesia and Surgical Outcomes、Colorectal Cancer Surgical Treatments

BACKGROUND: Colorectal cancer (CRC) is one of the most common cancers and CRC patients are among the most common intensive care unit (ICU) admitted cancer patients. However, their prognosis and evaluation methods are rarely studied. AIM: To determine the short-term mortality outcome and identify the potential prognostic factors of CRC cancer patients admitted to the ICU. METHODS: A multicenter cross-sectional study was performed from May 10, 2021 to July 10, 2021 at the ICU departments of 37 cancer specialized hospitals in China, and included patients aged ≥ 14 years with ICU duration ≥ 24 hours. Clinical records of patients with a primary CRC diagnosis were reviewed. Patients were separated into groups according to 90-day survival. Characteristics between groups were compared. Univariate and multivariate regression tests were used to analyze the correlated factors of ICU outcomes. Predictive values of disease severity scores were assessed using receiver operating characteristic curve analysis. RESULTS: In total, 189 CRC patients were included in the study. The 90-day mortality was 12.2%. Patients who died showed differences compared to patients who survived mostly in terms of disease severity and ICU complications. It appears that patients admitted to the ICU from a clinical ward due to emergencies may have a higher risk of mortality while surgical management was associated with better survival. In multivariate analysis, only chemotherapy, elective surgery and conventional o...