Dose–Response Associations of Grip Strength and Gait Speed With Multidimensional Mental Health

作者：Jiapei Wei, Liming Zhang, Shengyi Li, Xucheng Wu, Xingqi Cao, Liying Chen, Zuyun Liu, Yangzhen Lu, Xuan Ge · 发表于：Aging Medicine · 年份：2025 · DOI：10.1002/agm2.70042 · 被引用次数：2 · 研究领域：Balance, Gait, and Falls Prevention、Nutrition and Health in Aging、Bone health and osteoporosis research

ABSTRACT Objectives We aimed to examine the dose–response associations of grip strength and gait speed with multidimensional mental health among Chinese adults. Methods Cross‐sectional data on 661 adults from the ZheJiang longitudinal Study of Healthy Aging (JASHA) were utilized. Grip strength and gait speed were measured during physical examinations. Multidimensional mental health, covering cognitive function (the Auditory Verbal Learning Test (AVLT), the Montreal Cognitive Assessment (MoCA) test, and the Digit Symbol Substitution Test (DSST)), depressive symptoms (the Center for Epidemiologic Studies Depression (CES‐D) Scale), and psychological distress (the Perceived Stress Scale (PSS)), were assessed via standard questionnaires. Multivariable linear regression models and restricted cubic splines were applied to examine these associations. Results We found linear dose–response associations of grip strength and gait speed with most dimensions of mental health. For instance, higher grip strength was positively associated with higher cognitive function scores (AVLT_N3: β = 0.084, standard error (SE) = 0.032; DSST: β = 0.246, SE = 0.073 for per unit increase in grip strength) and lower CES‐D scores ( β = −1.265, SE = 0.626). Similarly, higher gait speed was associated with higher cognitive function scores (AVLT_N3: β = 2.882, SE = 0.860; MoCA: β = 0.996, SE = 0.499 for per unit increase in gait speed), lower CES‐D scores ( β = −1.448, SE = 0.692), and lower PSS scores ( β = −2...