Visible Light‐Mediated Radical Hydro‐Fluorosulfonylation of Propargylamines

作者：Hangbing Liu, Yingyin Zhang, Yi Duan, Qixin Jia, Tianyu He, Yu Zheng, Shenlin Huang · 发表于：Chemistry - An Asian Journal · 年份：2025 · DOI：10.1002/asia.202500866 · 研究领域：Sulfur-Based Synthesis Techniques、Radical Photochemical Reactions、Fluorine in Organic Chemistry

Abstract Presented herein is a straightforward synthesis of γ ‐amino alkenylsulfonyl fluorides from readily available propargylamines. The reaction proceeds through a radical hydro‐fluorosulfonylation of propargylamines under visible light irradiation. Preliminary mechanistic studies demonstrate that the fluorosulfonyl radicals are generated by the single electron transfer event of the electron donor − acceptor (EDA) complex involving FSO 2 Cl, a silver salt, and the propargylamine substrate.