Global, regional, and national burden trends of spinal fractures from 1990 to 2021: a population-based study

作者：Zhizhong Shang, Yanhui Lu, Jiale He, Jiawei Di, Zifang Huang, Pan Zhou, Lang Mai, Ruijue Zhu, Yankui Liu, Mao Pang, Lei He, Bin Liu, Limin Rong · 发表于：International Journal of Surgery · 年份：2025 · DOI：10.1097/js9.0000000000003290 · 被引用次数：2 · 研究领域：Spinal Fractures and Fixation Techniques、Bone health and osteoporosis research、Hip and Femur Fractures

BACKGROUND: Spinal fractures have become a significant cause of health loss and an increasing disease burden due to their high incidence and disability risk. However, the current understanding of the disease burden and its trend remains limited, which hinders the effectiveness of public health interventions. METHODS: Data for this study were sourced from the standardized Global Burden of Disease (GBD) 2021 database. Various analytical methods, including trend analysis, correlation analysis, age-period-cohort analysis, frontier analysis, health inequality analysis, and predictive analysis, were used to explore the current status and trends of the disease burden associated with spinal fractures. RESULTS: From 1990 to 2021, the age-standardized rate (ASR) of spinal fractures globally showed a downward trend, and this trend is expected to continue in the future. However, the absolute number of spinal fracture cases has steadily increased. Since 2018, the rate of decline in the age-standardized prevalence rate and years lived with disability has slowed. In 2021, there were 7.4975 million new cases of spinal fractures globally, with 5.3714 million existing patients, resulting in 546 000 years lived with disability. Significant disease burden inequalities were observed across different regions, with a notable increase in the burden as the Socio-Demographic Index (SDI) rises. High-SDI regions and countries faced the most severe disease burden. The ASR remained low for individuals und...