GPX1-driven selenium nanoplatform reprograms MAMs-mediated organelle crosstalk to reverse inflammatory adipose expansion in thyroid eye disease

作者：Yao Tan, Feng Zhang, Jiamin Cao, Lemeng Feng, Bingyu Xie, Limo Gao, Xiangdong Chen, Zuyun Yan, Wei Xiong · 发表于：Theranostics · 年份：2025 · DOI：10.7150/thno.117582 · 被引用次数：6 · 研究领域：Redox biology and oxidative stress、Nanoplatforms for cancer theranostics、Adenosine and Purinergic Signaling

Se@LNT offers the first MAMs-targeted nanotherapy for TED by reprogramming organelle crosstalk, restoring metabolic-immune homeostasis, and modifying disease progression at the subcellular level.