The impact of sleep deprivation on the functional connectivity of auditory-related brain regions

作者：Peng Zhang, Kai Wen, Huifeng Liu, Jing Wang, Qin Han, Fangfang Liu, Xiechuan Weng, Fan Xu · 发表于：Brain Research Bulletin · 年份：2025 · DOI：10.1016/j.brainresbull.2025.111563 · 被引用次数：2 · 研究领域：Sleep and Wakefulness Research、EEG and Brain-Computer Interfaces、Neural dynamics and brain function

This study explored the effects of 36-hour acute sleep deprivation on the functional connectivity of auditory-related brain regions in healthy young males, examining its associations with alertness and emotional states. Sixty participants were assessed before and after sleep deprivation using psychomotor vigilance tasks, sleepiness scales, mood scales, and resting-state fMRI. The findings indicated significant changes in the functional connectivity of auditory-related brain regions, involving multiple cognitive, emotional, and motor areas. Further correlation analysis revealed a complex relationship between auditory-related brain regions and alertness, sleepiness, and mood. This study provides new evidence on how sleep deprivation influences auditory-related brain function. • The acute sleep deprivation can negative affected not only the functional connectivity of auditory-related brain regions in healthy young males, but also on emotional and cognition process. • Further correlation analysis revealed a complex relationship between auditory-related brain regions and alertness, sleepiness, and mood.