American Association for Bronchology and Interventional Pulmonology (AABIP) Evidence-Based Guidelines on Bronchoscopic Diagnosis and Staging of Lung Cancer

作者：Russell Miller, Ara A. Chrissian, Fayez M. Kheir, Mājid Shafiq, Abigail T. Chua, Neal Navani, Francisco Aécio Almeida, Abdul Hamid Alraiyes, Paul Arthur Bain, Christina Bellinger, Cherng H. Chao, George Z. Cheng, Rebecca Cloyes, Javier I. Diaz-Mendoza, David M. DiBardino, Erik E. Folch, Laura Frye, Yaron B. Gesthalter, Thomas R. Gildea, Amit Goyal, Karen M. Heskett, Van K. Holden, Moïshe Liberman, Christopher J. Manley, Nikhil K Meena, Catherine L. Oberg, Jasleen Kaur Pannu, Edward M. Pickering, Michal Šenitko, Jo-Anne O. Shepard, Thomas Vandemoortele, Atul C. Mehta, Kazuhiro Yasufuku · 发表于：Journal of Bronchology & Interventional Pulmonology · 年份：2025 · DOI：10.1097/lbr.0000000000001034 · 被引用次数：13 · 研究领域：Lung Cancer Diagnosis and Treatment、Tracheal and airway disorders、Delphi Technique in Research

BACKGROUND: Lung cancer remains a predominant cause of cancer-related deaths worldwide, and there are notable geographic and institutional differences in both diagnostic and staging approaches. To address this, the American Association for Bronchology and Interventional Pulmonology (AABIP) convened a multidisciplinary committee to craft evidence-based and evidence-informed recommendations for diagnosing peripheral pulmonary nodules and performing convex probe endobronchial ultrasound (CP-EBUS)-guided mediastinal staging. METHODS: A modified Delphi method guided the creation and refinement of 9 Population, Intervention, Comparator, Outcome (PICO) questions. A systematic literature review, updated through March 2023, served as the basis for drafting recommendations. The panel used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach to assess the quality of evidence and relied on National Institute for Health and Care Excellence (NICE) language to express the strength of each recommendation. Where suitable, meta-analyses were completed; otherwise, systematic reviews and consensus among experts provided the evidence for guidance. RESULTS: Nine recommendations were ultimately proposed: 6 were supported by meta-analyses and 3 by systematic reviews. The topics include comparing diagnostic yield and complication rates between peripheral bronchoscopy and transthoracic needle biopsy, the use of multiple biopsy instruments and the role of rapid on-sit...