The strategic planning for scientific innovation based on clinically advantageous diseases in traditional Chinese medicine: Lupus nephritis in children

作者：Xia Zhang, Xianqing Ren, Chun Song, Wensheng Zhai, A Ma, Hong Xu, Ying Ding · 发表于：World Journal of Integrated traditional and western Medicine（WJIM) · 年份：2025 · DOI：10.70976/j.2096-0964.wjim-2025-0016 · 研究领域：Systemic Lupus Erythematosus Research、Science, Research, and Medicine

Abstract Pediatric lupus nephritis (LN) is a challenging and severe condition in pediatrics. Traditional Chinese medicine (TCM) has shown significant advantages in improving immune disorders, reducing recurrence rates, and mitigating the toxic side effects of Western medications. However, it faces challenges such as the lack of a unified TCM syndrome differentiation system, insufficient standardization of dynamic syndrome differentiation, an incomplete efficacy evaluation system, and a lack of precise intervention methods. This study focuses on the clinical advantages of TCM. On 1 September, 2024, the 35th Clinical Advantage Disease Series Salon was held in Zhengzhou, discussing the advantages of TCM and integrated Chinese-Western medicine in treating pediatric LN. Experts in TCM and integrated Chinese-Western medicine, along with interdisciplinary researchers, conducted extensive and in-depth discussions. They proposed specific recommendations for TCM and integrated Chinese-Western medicine in treating pediatric LN and reached a consensus. Based on this, the study analyzes the challenges in treating pediatric LN from the perspective of its development patterns, and summarizes three key areas and six research directions to highlight the advantages of TCM and integrated Chinese-Western medicine in treating pediatric LN. It focuses on three key areas: The construction of a TCM system for pediatric LN, the prevention and treatment of complications, and chronic disease managemen...