Undetectable=Untransmittable Perception and Its Association with Sexual Risk Behaviors and Potential Physical and Psychological Benefits Among People Living with HIV/AIDS in Hunan, China

作者：Yuqiong Duan, Yixuan Li, Ziqi Qin, Pingwu Wang, Tao Liu, Honghong Wang, Xueling Xiao · 发表于：Patient Preference and Adherence · 年份：2025 · DOI：10.2147/ppa.s544362 · 被引用次数：3 · 研究领域：HIV/AIDS Research and Interventions、HIV Research and Treatment、HIV-related health complications and treatments

Purpose: Undetectable = Untransmittable (U=U) is the scientific consensus that people living with HIV (PLWH) who maintain an undetectable viral load cannot sexually transmit HIV to others. This study aimed to explore the status of PLWH's perception of U=U (including knowledge, attitude, and acceptance) and the relationships with their sexual behaviors and potential physical and psychological benefits (satisfaction of health, depression, self-stigma, quality of life, ART adherence, viral load and CD4+ cell level). Patients and Methods: We analyzed data from 730 PLWH aged 18 years or older from the outpatient clinic at the Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, between October 2021 and January 2022. Data were collected using a structured, anonymous, paper-based questionnaire. It gathered information on U=U perception, sexual risk behaviors, potential physical and psychological benefits and socio-demographic and clinical characteristics. To examine associations between U=U perception and sexual risk behaviors and potential physical and psychological benefits, for categorical outcome variable, multiple logistic regression was adopted for the CD4+ cells and HIV viral load level; for count outcome variable, generalized linear model (GLM) with Poisson regressor was used for sexual risk behaviors; and since all the other response variables were skewed, GLM with Gamma regressor was used. Results: The mean age of the participants was 33.6 ...