Representation of top-down versus bottom-up attention in the right dorsolateral prefrontal cortex and superior parietal lobule

作者：Qiuzhu Zhang, Wenjuan Li, Tingting Zhang, Ronglong Xiong, Junjun Zhang, Zhenlan Jin, Ling Li · 发表于：Behavioral and Brain Functions · 年份：2025 · DOI：10.1186/s12993-025-00297-8 · 被引用次数：7 · 研究领域：Neural and Behavioral Psychology Studies、Spatial Neglect and Hemispheric Dysfunction、Functional Brain Connectivity Studies

BACKGROUND: Visual selective attention can be categorized into top-down (goal-driven) and bottom-up (stimulus-driven) attention, with the fronto-parietal network serving as the primary neural substrate. However, fewer studies have focused on the specific roles of the right dorsolateral prefrontal cortex (DLPFC) and superior parietal lobule (SPL) in top-down and bottom-up attention. This study aimed to investigate the activity and connectivity of the right DLPFC and SPL in top-down and bottom-up attention. METHODS: Visual pop-out task mainly induces bottom-up attention, while the visual search task mainly induces top-down attention. Fifty-four participants completed the pop-out and search tasks during functional magnetic resonance imaging (fMRI) scanning. We used univariate analyses, multivariate pattern analyses (MVPA), and generalized psychophysiological interaction (gPPI) to assess activity and functional connectivity. RESULTS: Univariate analyses revealed stronger activation in the right DLPFC and SPL during the search > pop-out condition. The activation of the DLPFC was driven by its deactivation in the pop-out task, whereas the SPL showed significant activation in both tasks. MVPA demonstrated that activation patterns in the right DLPFC and SPL could distinguish between the pop-out and search tasks above chance level (0.5), with the right SPL exhibiting higher classification accuracy. The gPPI analyses showed that higher functional connectivity between the two seeds (rig...