Delphi consensus on melasma management by international experts and pigmentary disorders society

作者：Rashmi Sarkar, Seemal R. Desai, Surabhi Sinha, Sunil Dogra, María Ivonne Arellano‐Mendoza, Pallavi Ailawadi, Sanjeev Aurangabadkar, Ediléia Bagatin, Shyamanta Barua, Mala Bhalla, Daniel Pinho Cassiano, Tânia Ferreira Cestari, Anupam Das, Johannes Flores Dayrit, Ncoza Cordelia Dlova, Cheng-Che Eric Lan, Nada Elbuluk, Ana Cláudia Cavalcante Espósito, Evangeline B. Handog, Soumya Jagadeesan, Saloni Katoch, Muthu Sendhil Kumaran, Prasad Kumarasinghe, Maria Juliet Macarayo, Hélio Amante Miot, Venkataram N. Mysore, Vignesh Narayan R, Sang Ho Oh, Thierry Passeron, Mauro Picardo, Indrashis Podder, Soumya Sachdeva, Aseem Sharma, Richa Sharma, Vijay Kumar Somani, Bhavesh Swarnkar, Susan C. Taylor, Devinder Mohan Thappa, Keshavamurthy Vinay, Henry W. Lim · 发表于：Journal of the European Academy of Dermatology and Venereology · 年份：2025 · DOI：10.1111/jdv.70066 · 被引用次数：18 · 研究领域：Dermatologic Treatments and Research、Acne and Rosacea Treatments and Effects、Laser Applications in Dentistry and Medicine

BACKGROUND: Melasma, an acquired hyperpigmentation disorder, affects individuals of all ethnicities. Its multifactorial aetiology, high recurrence rates and psychosocial impact complicate management and necessitate comprehensive, evidence-based recommendations. OBJECTIVES: The objective was to develop an international consensus on the diagnosis and management of melasma by synthesizing expert opinions and the latest scientific evidence. METHODS: This consensus was developed using a modified Delphi approach. A core group of two senior dermatologists who were experts in pigmentary disorders guided the process, and a diverse panel of 38 dermatologists with a special interest in pigmentary disorders from 11 countries (Australia, Brazil, France, India, Italy, Mexico, Philippines, South Africa, South Korea, Taiwan and the USA) participated in three rounds of surveys and discussions, under the aegis of the Pigmentary Disorders Society (PDS). A literature search of articles published between 2014 and 2024 identified key studies that were graded using the Oxford levels of evidence (2009). Consensus statements were drafted, refined and finalized based on expert feedback. Responses were assessed using a 5-point Likert scale, with predefined thresholds for high (≥75%), moderate (55%-74%) and low (<55%) agreement. RESULTS: The consensus development process started with 34 statements, and at the end of the third round of the Delphi process, 21, 4 and 1 statement reached high, moderate and ...