Research Communication: The Cumulated Spontaneous Portosystemic Shunts ( SPSS ) Area Decreases After TIPS and Impacts on Prognosis

作者：Marlene Hintersteininger, Theresa Bucsics, Susanne Riegler, Nina Dominik, Georg Kramer, Christian Sebesta, Paul Thöne, Ulrika Asenbaum, Lukas Reider, Maria Schoder, M Trauner, Mattias Mandorfer, Thomas Reiberger, Lukas Hartl, Katharina Lampichler · 发表于：Alimentary Pharmacology & Therapeutics · 年份：2025 · DOI：10.1111/apt.70381 · 被引用次数：2 · 研究领域：Liver Disease and Transplantation、Liver Disease Diagnosis and Treatment、Organ Transplantation Techniques and Outcomes

ABSTRACT We evaluated the dynamics of spontaneous portosystemic shunts (SPSS) after transjugular intrahepatic portosystemic shunt (TIPS). Ninety patients with covered TIPS placement and contrast‐enhanced CT scans before and after TIPS were included. Total SPSS area and total shunt area (including TIPS) were assessed. Median SPSS area (67.2–15.7 mm 2 ; p < 0.001) decreased after TIPS, while total shunt area remained unchanged (67.2–75.8 mm 2 ; p = 0.170). Relative SPSS area decrease was an independent protective factor for mortality (asHR: 0.19; 95% CI: 0.04–0.88; p = 0.034). In conclusion, SPSS decrease after TIPS and relative SPSS area change is independently linked to survival, while total shunt area remains unaltered.