Multimodal predictive model for strangulation risk in adhesive small bowel obstruction using deep learning and electronic health record data

作者：Han Wang, Jing Wu, Xianglin Ding, Zhongzhou Ruan, Shiqi Zhu, Yu Wang, Lihe Liu, Jiaxi Lin, Jinzhou Zhu, Xin Chen · 发表于：Journal of International Medical Research · 年份：2025 · DOI：10.1177/03000605251378951 · 被引用次数：3 · 研究领域：Intestinal and Peritoneal Adhesions、Hernia repair and management、Appendicitis Diagnosis and Management

AimsThis study aimed to develop and validate a multimodal predictive model for the risk of strangulation in adhesive small bowel obstruction by integrating deep learning-based computed tomography imaging features and clinical electronic health records.MethodsA retrospective, observational, multicenter study was conducted across three hospitals, with data from 225 patients used for model development and 123 patients for external validation. A three-dimensional convolutional neural network with a ResNet50 backbone was used to segment abdominal regions from computed tomography scans and classify strangulation risk. The multimodal model integrated deep learning predictions with top electronic health record features using the XGBoost algorithm; global and local interpretability were achieved through variable importance ranking and local interpretable model-agnostic explanations.ResultsThe multimodal model demonstrated superior performance in predicting strangulation within 7 days of admission, achieving an area under the curve of 0.915 in the training set and 0.912 in the test set, outperforming single-modality models. Calibration plots showed good alignment between predicted and observed outcomes, decision curve analysis demonstrated significant clinical utility, and net reclassification improvement confirmed that deep learning enhanced the model's predictive ability.ConclusionThis study highlights the potential of multimodal artificial intelligence combined with clinical data to...