Structural Insights Into the Role of RxLR Effectors in the Arms Race Between Oomycetes and Plants

作者：Yang Liu, Yang Zheng, Xin Zhou, Hossein Ghanizadeh, Dong Wang, Pei Wang, Mo Cheng, Jia Yin Liu, Jia Yin Liu, Xiu Ling Chen, Y. Zhang, Jun Feng Liu, Jun Feng Liu, Ao Xue Wang · 发表于：Molecular Plant Pathology · 年份：2025 · DOI：10.1111/mpp.70138 · 被引用次数：5 · 研究领域：Plant-Microbe Interactions and Immunity、Plant Pathogens and Fungal Diseases、Plant Pathogenic Bacteria Studies

Oomycetes threaten food security, with RxLR effectors playing a key role in their pathogenesis by modulating host-pathogen signalling and suppressing plant immune responses. A growing body of research has elucidated how RxLR effectors manipulate plant immune responses to achieve successful infection. Despite progress, the correlation between the structure and function of oomycete RxLR effectors is not fully understood. This review consolidates existing knowledge on the structure-function relationships of resolved effectors, offering a framework to understand their mechanisms during host-pathogen interactions and proposing insights for engineering resistant crop varieties.