Recent Advances of Luminescence Mechanisms and Biomedical Applications of Mechanoluminescent Materials

作者：Miao Yang, Yajun Gao, Xueping Long, F. Yang · 发表于：Chinese Journal of Luminescence · 年份：2025 · DOI：10.37188/cjl.20250026 · 被引用次数：3 · 研究领域：Nanoplatforms for cancer theranostics、Luminescence and Fluorescent Materials、Facial Trauma and Fracture Management

Abstract： Since the discovery of mechanoluminescence， it has undergone decades of development and has been widely applied in various fields， including sensing， anti-counterfeiting， and structural detection.However， the application of mechanoluminescent materials in biomedical fields is still in its early stages， with relatively few reports available.This paper first introduces advanced strategies for synthesizing mechanoluminescent materials and system • atically discusses several typical mechanoluminescence mechanisms， with a focus on trap-controlled mechanolumi• nescence.Additionally， it presents the recently developed novel mechanoluminescence models based on chemilumi• nescence and bioluminescence.Furthermore， this paper provides a comprehensive overview of the applications of mechanoluminescent materials in biomedical fields， including biosensing， near-infrared bioimaging， optogenetic neuromodulation， and disease treatment.Lastly， this paper summarizes the major challenges faced by mechanolumi• nescent materials in biomedical applications and proposes their future research directions.