Advanced Multifunctional Bioactive Glass Nanoparticles: from Tissue Repair to Theranostics

作者：Yanzi Zhao, Weipeng Qiang, Bo Lei · 发表于：Advanced Healthcare Materials · 年份：2025 · DOI：10.1002/adhm.202502192 · 被引用次数：3 · 研究领域：Bone Tissue Engineering Materials、Laser-Ablation Synthesis of Nanoparticles、Facial Trauma and Fracture Management

In recent years, multifunctional bioactive glass nanoparticles (BGNs) have received widespread attention in biomedical applications due to their highly bioactive properties, nanoscale structure, and various functions (tissue repair, bioimaging, tumor therapy, and anti-infection). This work reviews the recent progress of multifunctional BGNs on the physicochemical structure, preparation methods, functionalizing strategies, and biomedical applications from tissue repair to theranostics. The applications of functional BGNs in tissue repair, bioimaging, drug delivery, gene delivery, anti-infection therapy, tumor intervention, and the integrated therapeutic-repair platform are carefully summarized. Through the comprehensive analysis of multifunctional BGNs in terms of structural design, functional construction, and biomedical applications, the systematic references and theoretical support for the multidimensional optimization and precise clinical translations are provided.