Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial

作者：Xiaoxing Lai, Hongwei Zhu, Yonghua Cai, Baoyu Chen, Yang Li, Hongdi Du, Liping Zhang, Wenwen Wang, Shuxian Li, Xiaopeng Huo · 发表于：Frontiers in Aging Neuroscience · 年份：2025 · DOI：10.3389/fnagi.2025.1639245 · 被引用次数：6 · 研究领域：Frailty in Older Adults、Intensive Care Unit Cognitive Disorders、Older Adults Driving Studies

Objective This study aims to investigate the effects of exercise-cognitive dual-task training on frailty status, cognitive function, physical performance, and dual-task cognitive load in older adults with Cognitive frailty (CF) over a 16-week intervention period. Methods This randomized controlled trial enrolled older adults with CF at community health service center in Chaoyang District, Beijing, between February and March 2024. Participants were randomly assigned to either the dual-task training group or the health education group in a 1:1 ratio. The dual-task training group received an exercise-cognitive dual-task training program, while the health education group received information on CF, including its symptoms, risk factors, and non-pharmacological prevention and treatment strategies. The primary outcomes were frailty status, while the secondary outcomes included cognitive function, balance and gait function, walking ability, and dual-task cognitive load. Results A total of 72 participants (35 males) were enrolled, including 36 individuals (mean age: 74.81 ± 8.23 years, 17 males, mean BMI: 21.38 ± 2.83 kg/m 2 ) in the dual-task training group, and 36 individuals (mean age: 76.50 ± 7.75 years, 18 males, mean BMI: 22.18 ± 2.12 kg/m 2 ) in the health education group. Participants (n = 72) were 75.66 ± 7.9 years old; 48.6% (35/72) were male and 51.4% (37/72) were female. Following the intervention, the dual-task training group exhibited significant improvements compared to...