Autonomic function effects on postoperative sleep disorder: a prospective cohort study

作者：Yunda Fang, Yan Zhang, Gang Wang, Junjie Guan, Haifeng Wang, Mingyue Shao, Li Zeng, Zhiwei Jiang, Zhengming Deng · 发表于：International Journal of Surgery · 年份：2025 · DOI：10.1097/js9.0000000000002630 · 被引用次数：5 · 研究领域：Heart Rate Variability and Autonomic Control、Obstructive Sleep Apnea Research、Sleep and Work-Related Fatigue

BACKGROUND: Early identification of patients at risk of developing postoperative sleep disorders (PSD), which is a common complication after surgery, is an essential step in reducing surgical stress and is an important part of enhanced recovery after surgery. OBJECTIVE: In this study, we used a smart patch to explore heart rate variability (HRV), reflecting autonomic nervous system regulation, as potential PSD digital biomarkers and develop a prognostic model for the early identification of PSD. METHODS: We assessed 120 h of continuous HRV in a separate sample of 51 patients who underwent radical surgery for gastrointestinal cancer with and without PSD. RESULTS: By analyzing the 120-h HRV data of the two groups, we found that patients with PSD exhibited lower parasympathetic tone and longer dysregulated autonomic circadian rhythms. The area under the curve of the risk factor prediction model established by HRV parameters was 0.815; sensitivity was 0.909; specificity was 0.621; and the Youden index was 0.530. CONCLUSION: This research supports the utility of HRV as a non-invasive diagnostic tool, emphasizing its importance in perioperative management of sleep quality and potential to expand its use during the perioperative period.