Design and development of a transmit RF coil for large field of view hyperpolarized 13C imaging

作者：Albert Chen, Takashi Ishiguro, Fraser Robb, D. Chris Anderson, Tony Thomas, Jana Vincent, Venkata Rao Malasani, Victor Taracila, Thomas Grafendorfer, Edward Baus, Thomas Stickle, Atsushi Nozaki, Justin Y. C. Lau, Arnaud Comment, Charles H. Cunningham, Kayvan R. Keshari · 发表于：Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 年份：2025 · DOI：10.58530/2025/4477 · 研究领域：Advanced NMR Techniques and Applications、Superconducting Materials and Applications、Atomic and Subatomic Physics Research

Motivation: To bring hyperpolarized 13C body imaging to its full potential. Goal(s): Develop a 13C transmit coil that can provide large FOV coverage with uniform B1+ field, while minimizing impact to patient access and comfort. Approach: An asymmetric 8 rung high-pass birdcage coil was designed to sit directly on the patient cradle. The prototype coil was constructed as a flat base along with a detachable top cage. Results: The B1 maps acquired using the 13C birdcage coil in T/R mode showed good uniformity. The coil also performed as expected as a Tx only coil. Impact: The 13C transmit coil developed in this project provides uniform RF excitation across a large FOV without compromising patient comfort and the 1H imaging. It will be an integral element for routine clinical HP 13C metabolic imaging in the future.