Integration of fishbone deep processing technology with animal experiments on inventive calcium supplements for aquatic circular economy

作者：E. Wang, C. Huang, Kuang Ting Huang, Wen Ling Shih, Tzu-Chiu Yeh · 发表于：Applied Food Research · 年份：2025 · DOI：10.1016/j.afres.2025.101334 · 被引用次数：3 · 研究领域：Protein Hydrolysis and Bioactive Peptides、Food Industry and Aquatic Biology、Insect Utilization and Effects

Calcium is a crucial health element at all stages and animal byproduct bones have been deemed as suitable supplement products to convert nutrition facts for people in need. On the other hand, the higher the byproduct utilization rate and value created, the more the main products contribution to the aquatic circular economy and the health benefits of calcium products. However, the ratio of processing byproducts discarded or sold at low prices has always remained at high levels because of drug or heavy metal residues in most animal species, the difficulty of obtaining bones, gaps in processing technology, and lack of validation of products as the main factor in terms of calcium components. As such, calcium supplements are primarily being chemically synthesized and natural calcium products account for only a small share of the market. This study focuses on precise calcium supplementation for public health by using grouper fishbone byproducts as raw materials. The fishbone byproducts are firstly pulverized to powder through creative processing technology and a series of verifications are carried out for the presence of heavy metals, drug residues, and the content of calcium, potassium, phosphorus, magnesium, zinc, selenium, and other nutrients. Additionally, an animal experiment is conducted to verify the effect on calcium-related health elements such as osteocalcin, cholesterol, alkaline phosphatase, serum calcium, and serum phosphorus. The experimental design followed the Minis...