Beyond symptom improvement: transdiagnostic and disorder‐specific ways to assess functional and quality of life outcomes across mental disorders in adults

作者：Christoph U. Correll, Samuele Cortese, Marco Solmi, Tommaso Boldrini, Koen Demyttenaere, Katharina Domschke, Paolo Fusar‐Poli, Philip Gorwood, Philip D. Harvey, Richard S.E. Keefe, Christine Knaevelsrud, Roman Kotov, Laura Nohr, Taeho Greg Rhee, David Roe, Matthias Rose, Lon S. Schneider, Mike Slade, Dan J. Stein, Charlene Sunkel, Roger S. McIntyre · 发表于：World Psychiatry · 年份：2025 · DOI：10.1002/wps.21338 · 被引用次数：24 · 研究领域：Schizophrenia research and treatment、Bipolar Disorder and Treatment、Mental Health Treatment and Access

Improving meaningful outcomes is the main goal of clinical care for mental disorders. Traditionally, the focus in clinical research and practice has been on outcome domains that refer to symptom severity or service use (e.g., hospitalization), relate to categorical diagnoses, and favour clinician-rated measures. More recently, self-rated and dimensional as well as transdiagnostic outcome domains have gained traction, and functioning, quality of life and well-being/life satisfaction, along with the construct of personal recovery, have become a stronger focus. These key multidimensional outcome domains need to be properly defined and assessed. Further, the concepts of "functional" and "personal" recovery need to be differentiated. "Functional recovery" is defined by observed functioning across the domains of self-care, social interactions, leisure time activities, and educational or vocational activities. "Personal recovery" involves the subjective sense of living a personally meaningful life, irrespective of whether symptoms continue, or ongoing/intermittent support is needed. Despite the multi-stakeholder relevance of these outcome domains, no comprehensive account of how to measure them is available. To fill this gap, we provide here an overview of the main tools to assess functioning, quality of life/well-being/life satisfaction, and personal recovery outcomes across mental disorders in adults, aiming to also identify additional needs that should be addressed. We identified...