The Prevalence of Symptomatic Dermographism: Results of the International UCARE PREVALENCE ‐D Study

作者：Kanokvalai Kulthanan, Jonathan A. Bernstein, Michael Rudenko, Pascale Salameh, Chulaluk Komoltri, Esra Adışen, Salma Al-Abri, Mona Al‐Ahmad, Nasser Al‐Ahmed, Bushra Al Hinai, Anastasiia Allenova, Saad Alshareef, Nattha Angkoolpakdeekul, Rand Arnaout, Joanna Bartosińska, Iván Chérrez-Ojeda, Leena Chularojanamontri, Paulo Ricardo Criado, Luís Felipe Ensina, Roberta Fachini Jardim Criado, César A. Galván, Ana M. Giménez‐Arnau, Kiran Godse, Maia Gotua, Naoko Inomata, Nuttagarn Jantanapornchai, Chang‐Gyu Jung, Alicja Kasperska−Zając, Maryam Khoshkhui, Pavel Kolkhir, Dorota Krasowska, Jomgriditip Laomoleethorn, Antonina Maiorowa, Raisa Meshkova, Dragan Mijakoski, Melba Muñoz, Yanisorn Nanchaipruek, Iman Nasr, Rabia Öztaş Kara, Waratchaya Panjapakkul, Teerapat Paringkarn, Indrashis Podder, Karla Robles‐Velasco, Isabel Rosmaninho, Ana Presa, Chuda Rujitharanawong, Phuwakorn Saengthong‐aram, Rana Tafrishi, Natasa Teovska‐Mitrevska, Papapit Tuchinda, Teerapat Wannawittayapa, Anushka Wilson, Young‐Min Ye, Anna Zalewska‐Janowska, Marcus Maurer, Torsten Zuberbier · 发表于：Allergy · 年份：2025 · DOI：10.1111/all.70047 · 被引用次数：7 · 研究领域：Urticaria and Related Conditions、Mast cells and histamine、Dermatology and Skin Diseases

BACKGROUND: The prevalence of symptomatic dermographism (SD) in the general population remains unclear. This study aimed to internationally estimate the prevalence of SD and two other dermographic subtypes-physiological red dermographism and simple urticarial dermographism-among adults worldwide. METHODS: The PREVALENCE-D (Prevalence Estimation of Dermographism) study was the largest international, cross-sectional, internet-based investigation conducted by the Urticaria Centers of Reference and Excellence of the Global Allergy and Asthma Excellence Network from 2021 to 2024. A world expert-designed questionnaire was completed by participants from 28 centers across 19 countries to diagnose SD. Participants were recruited into three age groups (18-24, 25-60, and > 60 years), with ≥ 1000 individuals per group per country. We calculated sex- and age-adjusted prevalence estimates internationally and by country, with 95% confidence intervals. RESULTS: Among 59,543 participants worldwide, those with SD had an adjusted point prevalence of 3.20% (95% confidence interval [CI] 2.68%-3.73%) and a lifetime prevalence of 5.94% (95% CI 5.32%-6.56%). The 25-60 years group presented the highest prevalence. Females had higher rates than males, with statistically significant differences across all age groups for both point and lifetime prevalence. Physiological red dermographism had an adjusted point prevalence of 10.02% (95% CI 9.48%-10.55%) and a lifetime prevalence of 33.47% (95% CI 32.01%-3...