Synthesis, Crystal Analyses, and Chiroptical Properties of Coumarin-Containing Helicenes

作者：Yanjie Zhu, Guofeng Chen, Jiawei Gao, Chengxiu Wang, Shiyong Li, Ran Zhang, Jinchong Xiao · 发表于：Organic Letters · 年份：2025 · DOI：10.1021/acs.orglett.5c03046 · 被引用次数：3 · 研究领域：Synthesis and Properties of Aromatic Compounds、Molecular spectroscopy and chirality、Photochromic and Fluorescence Chemistry

Four novel coumarin-containing arenes bearing a [5]/[6]helicene unit ( 5, 7, 11, and 13 ) have been readily synthesized and structurally verified by X-ray crystallographic analysis. The chiral resolution of molecules 7, 11, and 13 has enabled a detailed investigation of their chiroptical properties and the kinetics of enantiomerization, manifesting that the [6]helicenes 11 and 13 exhibit a more enhanced chiroptical response compared to [5]helicene 7 .