Single-cell analysis of Barrett’s esophagus and carcinoma reveals cell types conferring risk via genetic predisposition

作者：Marten C Wenzel, Pouria Dasmeh, Patrick Sven Plum, Ann-Sophie Giel, Sascha Hoppe, Marek Franitza, Christoph Jonas, René Thieme, Yue Zhao, Dominik Heider, Claire Palles, Rebecca Claire Fitzgerald, Christiane J. Bruns, Reinhard Buettner, Alexander Quaas, Ines Gockel, Carlo Maj, Seung‐Hun Chon, Johannes Schumacher, Axel M. Hillmer · 发表于：Cell Genomics · 年份：2025 · DOI：10.1016/j.xgen.2025.100980 · 被引用次数：2 · 研究领域：Single-cell and spatial transcriptomics、Esophageal Cancer Research and Treatment、IL-33, ST2, and ILC Pathways

memory T cells seem to contribute to BE development. The diagnostic value of markers characterizing the cell types and cellular processes should be explored for EAC prediction.