Staging laparoscopy for gastric cancer: European consensus

作者：Sander J M van Hootegem, Niels A.D. Guchelaar, Karen van der Sluis, Lianne Triemstra, Stefan Mönig, Karol Rawicz‐Pruszyński, Riccardo Rosati, Paolo Morgagni, Maria Erodotou, Leonardo Solaini, Giovanni De Manzoni, Wojciech Polkowski, Francesco Puccetti, Simone Giacopuzzi, Suzanne S. Gisbertz, Jimmy Bok Yan So, Jelle P. Ruurda, Pieter C. van der Sluis, Sjoerd M. Lagarde, Johanna W van Sandick, Bas P. L. Wijnhoven, Other Members of the IGCA European Chapter Collaborative Group on Staging Laparoscopy for Gastric Cancer, Alexander A. F. A. Veenhof, Adam Zeyara, Alan Patrick Ainsworth, Alessia Malagnino, Alexander W. Phillips, Anastasios Kottikias, Andrew Davies, Arto Kokkola, Bo Jan Noordman, Carlo Vallicelli, Carolina Canhoto, Cecília Monteiro, Cláudia Neves Marques, Claudio Belluco, Daniel Reim, Daniele Marrelli, Daromir Godula, David James, Davide Zattoni, Dimitrios Schizas, Dimitrios Theodorou, Dionysios Dellaportas, Eelco B. Wassenaar, Eider Talavera-Urquijo, Fabio Uggeri, Fabrizio D’Acapito, Fausto Rosa, Federica Riccio, Francesco Abboretti, Geert A. Simkens, Gianluca Garulli, Gianmario Edoardo, Giovanni De Manzoni, Grard A. P. Nieuwenhuijzen, Guido Alberto Massimo Tiberio, Henk H. Hartgrink, Hanne Vanommeslaeghe, Hylke J.F. Brenkman, Ines Gockel, Ioannis Karavokyros, Ioannis Rouvelas, Jan-Willem Haveman, Jacopo Weindelmayer, Jan Willem T. Dekker, Jessie A. Elliott, Joos Heisterkamp, José Adelino Laborinhas Barbosa, José Freire, Koen J. Hartemink, Lapo Bencini, Lieven Depypere, Luca Provenzano, Lucia Moletta, L. Carbone, Luigina Graziosi, Mark I. van Berge Henegouwen, Magnus Nilsson, Marcel Schneider, Marco Milone, Maria Bencivenga, Marloes Emous, Mattia Berselli, Mauro Zago, Meindert N. Sosef, Michael Hareskov Larsen, Michele Manara, Michele Valmasoni, Michiel F.G. de Maat, Monica Gualtierotti, Monica Martin, Fahad Mahmood, Nezih Akkapulu, Paolo Morgagni, Paolo Parise, Paul Carroll, Paul M. Schneider, Pedro Azevedo Serralheiro, Ines Gockel, Radosław Pach, Raffaele De Luca, Renato Salvador, Renol M Koshy, Rita Alfieri, Sara Pollesel, Markus Schäfer, Sheraz R. Markar, Silvia Ministrini, Stefan Antonowicz, Stefania Angela Piccioni, Stefano Olmi, Stefano Rausei, Styliani Mantziari, Tania Triantafyllou, Víctor Turrado-Rodriguez, Wendy Kelder, Yannick Deswysen, Yves Borbély · 发表于：British journal of surgery · 年份：2025 · DOI：10.1093/bjs/znaf144 · 被引用次数：4 · 研究领域：Gastric Cancer Management and Outcomes、Gastrointestinal Tumor Research and Treatment、Minimally Invasive Surgical Techniques

Gastric cancer is the fifth most prevalent cancer and the third most common cause of cancer-related deaths globally1. Gastric cancer frequently metastasizes to the peritoneal cavity. The incidence of peritoneal metastases at the time of diagnosis, including free cancer cells in peritoneal washings, ranges from 15% to 32%, and its presence is associated with a poor prognosis2,3. Due to the low sensitivity of conventional imaging such as CT or PET-CT for peritoneal metastases, staging laparoscopy is performed to exclude small-volume macroscopic peritoneal dissemination or free cancer cells, and to assess the local resectability of the tumour4–6. Although staging laparoscopy has been part of diagnostic workup for patients with gastric cancer for over a decade, guidelines differ on patient selection and criteria of those at risk of peritoneal dissemination. Several guidelines limit its use to cT3/T4 tumours or gastric cancer with a high nodal burden (see supplementary material S3). In contrast, the National Institute for Health and Care Excellence (NICE) guideline recommends performing staging laparoscopy in all patients with gastric cancer7. Interestingly, all guidelines lack recommendations on how to perform staging laparoscopy, likely due to the significant variation in technical performance, which complicates comparison of procedure-based outcomes8. This inconsistency poses challenges when evaluating rates of peritoneal dissemination, limits the ability to understand the diag...