Structure Elucidation and Complete NMR Spectral Assignments of New Sesquiterpenes Isolated From Marine Derived Fungus Aspergillus sydowii ‐HB

作者：Baorui Teng, Sijing Liu, Dan Zhang, Xiujuan Fu, Siwei Chen, Hui Lei, Ya Yang · 发表于：Magnetic Resonance in Chemistry · 年份：2025 · DOI：10.1002/mrc.70035 · 被引用次数：3 · 研究领域：Microbial Natural Products and Biosynthesis、Marine Sponges and Natural Products、Fungal Biology and Applications

ABSTRACT Six sesquiterpene derivative compounds ( 1 – 6 ), including one new 7 R ‐sydowic acid ( 1 ) and five known compounds ( 2 – 6 ) were isolated from the secondary metabolites of Aspergillus sydowii ‐HB. The structures were determined by NMR spectroscopy and ESI‐MS analysis, and the configuration of compound 1 was confirmed through DP4 + calculation and NMR chemical shift. All the isolated compounds ( 1 – 6 ) were tested for their cytotoxic activities. The possible biosynthetic pathways for compounds ( 1 – 6 ) were also postulated.