Effectiveness of group-based multicomponent psychoeducational intervention on anxiety, depressive symptoms, quality of life, and coping among caregivers of children with cancer: A randomised controlled trial

作者：Lophina Phiri, H. Li, Patrick Phiri, Kai Chow Choi, Watipaso Wanda‐Kalizang'oma, Grace Nkhandwe · 发表于：International Journal of Nursing Studies · 年份：2025 · DOI：10.1016/j.ijnurstu.2025.105205 · 被引用次数：3 · 研究领域：Childhood Cancer Survivors' Quality of Life、Pediatric Pain Management Techniques、Family Support in Illness

BACKGROUND: Caring for a child with cancer is a stressful experience for caregivers because of the nature of cancer and the complexity of treatment, which predisposes them to negative psychological outcomes. Common negative psychological outcomes include anxiety and depressive symptoms. Caregivers also commonly report poor health-related quality of life and dysfunctional coping. OBJECTIVE: To evaluate the effectiveness of a group-based multicomponent psychoeducational intervention on anxiety, depressive symptoms, health-related quality of life, and coping among caregivers of children undergoing cancer treatment. DESIGN: A single-blind parallel randomised controlled trial. SETTING(S): Two major paediatric cancer centres in Malawi. PARTICIPANTS: Caregivers of children undergoing cancer treatment. METHODS: The intervention group underwent six weekly sessions of psychoeducational intervention, while the control group received the usual care. The primary outcome was anxiety and depressive symptoms, while secondary outcomes were health-related quality of life and coping. Data collection was conducted at baseline, immediately after the intervention and 3 months afterwards. A generalised estimating equation was used to analyse data. An intention-to-treat analysis was performed to minimise attrition bias. RESULTS: Overall, 118 participants were randomised to either the intervention group (59) or the control group (59). The intervention group showed a statistically significant reductio...