Discovery of novel xanthotoxin-pyridine quaternary ammonium derivatives with membrane-targeting mode of action as potential antimicrobials against methicillin-resistant Staphylococcus aureus

作者：Shengnan Xu, Miaomiao Zhang, Xinyu Xie, Yue Tian, Yan Wang, Xiaozhong Wang, Ruige Yang, Yong Guo · 发表于：European Journal of Medicinal Chemistry · 年份：2025 · DOI：10.1016/j.ejmech.2025.118139 · 被引用次数：13 · 研究领域：Antimicrobial Resistance in Staphylococcus、Antimicrobial Peptides and Activities、Microbial Natural Products and Biosynthesis