Comparison of clinical effects and patient satisfaction between ultra-pulsed CO₂ laser treatment and surgical excision in patients with facial basal cell carcinoma

作者：An-Chen Chen, Zheng Chen, Qi-chao Jian, Peng Zhang · 发表于：Frontiers in Surgery · 年份：2025 · DOI：10.3389/fsurg.2025.1628257 · 被引用次数：2 · 研究领域：Nonmelanoma Skin Cancer Studies、Dermatologic Treatments and Research、Reconstructive Facial Surgery Techniques

Background Basal cell carcinoma (BCC) commonly affects facial skin, with surgical excision being the usual treatment. However, surgery often leads to complications and slow healing, impacting quality of life. Recently, ultra-pulsed CO₂ laser has emerged as a minimally invasive option with good cosmetic results, but its effectiveness and patient satisfaction compared to surgery are still uncertain. Objective This study aims to compare the clinical outcomes and patient satisfaction between ultra-pulsed CO₂ laser treatment and surgical excision for patients with facial BCC. Methods A retrospective analysis was conducted on 100 patients with facial BCC treated at our dermatology department from January 2021 to January 2024.Among them, 50 patients received ultra-pulsed CO₂ laser treatment, while 50 underwent traditional surgical excision. We compared the tumor excision rates, incidence of postoperative complications, healing times, and patient satisfaction (assessed through a questionnaire) between the two groups. Results The clinical effective rate in the ultra-pulsed CO₂ laser group was 94.0%, compared to 90.0% in the surgical excision group, with no statistically significant difference between the two groups ( p > 0.05).Postoperative complications in the CO₂ laser group were primarily mild burns and inflammatory erythema, all of which resolved spontaneously within 1–2 days without treatment, with no serious adverse reactions reported. Recurrence rates were 4.00% (laser) ...