Design of peptide-based PAC1 antagonists combining molecular dynamics simulations and a biologically relevant cell-based assay

作者：Wenqin Xu, Abigail M Keith, Wenjuan Ye, Xin Hu, Noel Southall, Juan Marugán, Marc Ferrer, Mark J. Henderson, Patrick M. Sexton, Giuseppe Deganutti, Lee E. Eiden · 发表于：Biochemical Pharmacology · 年份：2025 · DOI：10.1016/j.bcp.2025.117300 · 被引用次数：2 · 研究领域：Neuropeptides and Animal Physiology、Receptor Mechanisms and Signaling、Hormonal Regulation and Hypertension