Preoperative easily misdiagnosed pure spinal epidural cavernous hemangioma: clinical-radiologic-pathologic correlations

作者：Jingwen Li, Zhongyin Guo, Yang Liu, Min Xu, Peng Wang, Feng Chen, Yue Zeng, Peng Peng · 发表于：Frontiers in Neurology · 年份：2025 · DOI：10.3389/fneur.2025.1615451 · 被引用次数：2 · 研究领域：Vascular Malformations Diagnosis and Treatment、Spinal Hematomas and Complications、Spinal Fractures and Fixation Techniques

Objective: Pure spinal epidural cavernous hemangiomas (PSECHs) are exceedingly rare vascular anomalies, often underreported and prone to misdiagnosis. This study aims to synthesize existing literature alongside seven cases from our institution to elucidate the clinical, imaging, and pathological characteristics of PSECHs for improving the clinical diagnosis and treatment of this disease. Methods: The clinical data of published literature and seven patients diagnosed with PSECHs admitted to the Department of Neurosurgery of Xiangyang Central Hospital from January 2013 to November 2022 were retrospectively analyzed for pre- and post-operative imaging findings, clinical manifestations, treatment history, pathologic characteristics, and treatment effects. Results: Approximately a hundred cases of PSECHs had been documented in the literature, with a clinical misdiagnosis rate reaching 91.3%. Among the seven patients studied, five were female, with a mean age of 49.4 years. In five cases, the lesions were located in the thoracic vertebral segment, while the cervical and lumbar vertebral segments each accounted for one case. One patient presented exclusively with radicular symptoms, four exhibited solely spinal cord symptoms, and two experienced both spinal cord and radicular symptoms. Two cases were initially misdiagnosed as meningiomas prior to surgery (2/7, 28.6%), with one case not accurately identified during the operation, leading to an erroneous aspiration as surgical blood s...