Neighborhood Social Vulnerability and Racial Disparities in Schizophrenia Spectrum Disorder Prevalence

作者：Deidre M. Anglin, Mark Olfson, Els van der Ven, Hans Oh, Roberto Lewis‐Fernández, Jordan DeVylder, Oladunni Oluwoye, Lisa B. Dixon, T. Scott Stroup, Heidi Guyer, Natalie Bareis · 发表于：American Journal of Psychiatry · 年份：2025 · DOI：10.1176/appi.ajp.20240906 · 被引用次数：2 · 研究领域：Schizophrenia research and treatment、Mental Health Treatment and Access、Health disparities and outcomes

OBJECTIVE: The study aim was to identify ethnoracial disparities in the prevalence of schizophrenia spectrum disorders (SSDs) and positive psychotic symptoms in the United States and examine the role of social neighborhood inequities. METHODS: Participants in the Mental and Substance Use Disorders Prevalence Study, a national household sample of nonelderly adults (N=4,764), were assessed by clinicians with the Structured Clinical Interview for DSM-5 (SCID-5) for SSDs (past year and lifetime), including schizophrenia, schizoaffective disorder, and schizophreniform disorder, and for psychotic symptoms. Weighted logistic regression models estimated ethnoracial differences in the prevalence of SSDs and psychotic symptoms in unadjusted models, age- and sex-adjusted models, and models further adjusted for a neighborhood Social Vulnerability Metric (SVM) score, a composite index of five social determinants of health domains. RESULTS: Compared to non-Hispanic White individuals, non-Hispanic Black individuals had a significantly higher prevalence of SSDs (4.1% vs. 1.2%; adjusted odds ratio=3.49, 95% CI=1.37, 8.91) and psychotic symptoms (9.3% vs. 4.9%; adjusted odds ratio=2.04, 95% CI=1.15, 3.63), and non-Hispanic multiracial individuals had a significantly higher prevalence of SSDs (5.6%; adjusted odds ratio=4.59, 95% CI=1.53, 13.76). Further adjustment for SVM score lowered the Black-White group difference for SSDs (adjusted odds ratio=2.49, 95% CI=0.63, 9.90) and psychotic symptoms...