Impact of Short‐Term Exposure to Ozone on Hospital Admissions for Multiple Cardiovascular Diseases: A Systematic Review and Meta‐Analysis

作者：Yu You, Juan Chen, Kai Wang, Tong Tong Wu, Lijun Bai, Ge Li, Shaowei Wu · 发表于：Journal of the American Heart Association · 年份：2025 · DOI：10.1161/jaha.124.037205 · 被引用次数：7 · 研究领域：Air Quality and Health Impacts、Climate Change and Health Impacts、Global Health Care Issues

Background The associations between short‐term exposure to ambient ozone (O 3 ) pollution and the risks of hospital admissions (an indicator for morbidity) for different subtypes of cardiovascular disease (CVD) remain unclear. Therefore, this study aimed to evaluate the associations between short‐term exposure to O 3 and the risks of hospital admissions for all‐cause CVD, arrhythmia, atrial fibrillation, cardiac diseases, heart failure, ischemic heart disease, myocardial infarction (MI), and stroke. Methods Four electronic databases, including PubMed, Web of Science, Scopus, and Embase, were searched for articles published up to December 21, 2023. Epidemiological studies reporting the associations between short‐term exposure to O 3 and the risks of hospital admissions for CVDs were included on the basis of stringent inclusion and exclusion criteria. The random‐effect model was applied to estimate pooled relative risk and 95% CIs. To identify potential effect modifiers, subgroup and meta‐regression analyses were also performed. Results A total of 111 articles with >65 million participants were included in the meta‐analysis. For a 10 μg/m 3 increase in short‐term exposure to O 3 , the relative risks of hospital admissions for MI and stroke were 1.0084 (95% CI, 1.0019–1.0151) and 1.0023 [95% confidence interval (CI), 1.0012–1.0034], respectively. Subgroup and meta‐regression analyses revealed that study area and national economic status could influence the impact of O 3 on di...