2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias

作者：François Mach, Konstantinos C. Koskinas, Jeanine E. Roeters van Lennep, Lâle Tokgözoğlu, Lina Badimón, Colin Baigent, Marianne Benn, Christoph J. Binder, Alberico L. Catapano, Guy De Backer, Victoria Delgado, Natalia Fabin, Brian A. Ference, Ian Graham, Ulf Landmesser, Ulrich Laufs, Borislava Mihaylova, Børge G. Nordestgaard, Dimitrios Richter, Marc S. Sabatine, ESC/EAS Scientific Document Group, Christian Mueller, Heinz Drexel, Ana Abreu, Marianna Adamo, Suleman Aktaa, Folkert W. Asselbergs, Antonio Baldini, Giuseppe Boriani, Margarita Brida, Marianne Brodmann, Edina Cenko, Nikolaos Dagres, Jörn F. Dopheide, Christoph Ebenbichler, Estelle Gandjbakhch, Diana A Gorog, Ioanna Gouni‐Berthold, Luigina Guasti, Bettina Heidecker, Borja Ibáñez, Stefan James, Peter Jüni, Marta Kałużna‐Oleksy, Konstantin A. Krychtiuk, Gregory Y H Lip, Roberto Lorusso, Felix Mahfoud, Marco Metra, Inge Moelgaard, João Morais, Lis Neubeck, Steven E. Nissen, Elena Osto, Klaus G. Parhofer, Leopoldo Pérez de Isla, Maurizio Pesce, Žaneta Petrulionienė, Eva Prescott, Ernst Rietzschel, Bianca Rocca, José F. Rodríguez‐Palomares, Xavier Rosselló, Anna Sannino, Anne Grete Semb, Jolanta M Siller-Matula, Thenral Socrates, Felix C. Tanner, Johann Wojta, Alberto Zambon, Katja Zeppenfeld, Nadia Laredj, Hamlet Hayrapetyan, Walter S. Speidl, Fuad Samadov, Philippe van de Borne, Zumreta Kušljugić, Arman Postadzhiyan, Hera Heracleous, Petr Ošťádal, Finn Lund Henriksen, Mohamed S. A. Mohamed, Margus Viigimaa, Markus Juonala, Franck Boccara, Archil Chukhrukidze, Oliver Weingärtner, Maria Marketou, Róbert Gábor Kiss, Axel F. Sigurðsson, Vincent Maher, Yaakov Henkin, Savina Nodari, Makhabbat Bekbossynova, Pranvera Ibrahimi, Erkin М Мirrakhimov, Sanda Jēgere, Samir Arnaout, Osama Bheleel, Jurgita Plisienė, Laurent Visser, Mark Abela, Victoria Ivanov, Aneta Bošković, Nazzi Mbarek, Maarten J.G. Leening, Marijan Bosevski, Elisabeth Kleivhaug Vesterbekkmo, Jacek Kubica, Jorge Ferreira, Dana Pop, Umberto Maria Stefanelli, Vojislav Giga, Daniel Pella, Zlatko Fras, Rosa Fernández-Olmo, Lennart Nilsson, Isabella Sudano, Mohamed Yassin Bani Marjeh, Faten Triki, Muzaffer Değertekin, Olena Mitchenko, Amitava Banerjee, Aleksandr B. Shek · 发表于：European Heart Journal · 年份：2025 · DOI：10.1093/eurheartj/ehaf190 · 被引用次数：457 · 研究领域：Lipoproteins and Cardiovascular Health、Diabetes, Cardiovascular Risks, and Lipoproteins、Health Systems, Economic Evaluations, Quality of Life

1. Preamble 3 2. Introduction 5 3. Estimation of total cardiovascular risk and implications for dyslipidaemia management 5 4. New low-density lipoprotein cholesterol-lowering therapies 9 5. Combination of lipid-lowering therapies during index hospitalization for acute coronary syndromes 11 6. Lipoprotein(a) 12 7. Hypertriglyceridaemia 13 8. Primary prevention in people with human immunodeficiency virus infection 14 9. Patients with cancer at high or very high chemotherapy-related cardiovascular toxicity risk 15 10. Dietary supplements 15 11. Evidence tables 16 12. Data availability statement 16 13. Author information 16 14. Appendix 16 15. References 17 Recommendation Table 1 — Recommendations for cardiovascular risk estimation in persons without known cardiovascular disease (see also Supplementary data online, Evidence Table 1) 9 Recommendation Table 2 — Recommendations for pharmacological low-density lipoprotein cholesterol lowering (see also Supplementary data online, Evidence Table 2) 11 Recommendation Table 3 — Recommendations for lipid-lowering therapy in patients with acute coronary syndromes (see also Supplementary data online, Evidence Table 3) 12 Recommendation Table 4 — Recommendations for measurement of lipoprotein(a) (see also Supplementary data online, Evidence Table 4) 12 Recommendation Table 5 — Recommendations for drug treatment of patients with hypertriglyceridaemia (see also Supplementary data online, Evidence Table 5) 14 Recommendation Table 6 — Recommenda...