Systematic interventions based on the stress-induced situation, affective, bodily, and cognitive reactions framework to mitigate psychological distress in lung cancer patients post-thoracoscopic surgery: a randomized clinical trial

作者：Lili Tang, Quanxing Liu, Yuexia He, Huanzhi Peng, Maoyu Luo, Hong Zheng, Qingling Zhang · 发表于：Frontiers in Psychology · 年份：2025 · DOI：10.3389/fpsyg.2025.1511622 · 被引用次数：3 · 研究领域：Cancer survivorship and care、Music Therapy and Health、Lung Cancer Diagnosis and Treatment

Objective To evaluate the efficacy of a multi-component intervention based on the Situational, Affective, Bodily, and Cognitive (SABC) stress-response model in reducing psychological distress and enhancing quality of life among post-thoracoscopic lung-cancer patients. Methods In this single-center, assessor-masked, parallel-group randomized controlled trial, 240 patients were randomized (1:1) to either a 12-month SABC intervention ( n = 120) or standard care ( n = 120) by means of computer-generated, sealed-envelope allocation. Outcome assessors were blinded to group assignment. The intervention comprised psycho-education, SABC-based skills training, a daily-habits checklist and scheduled follow-up. Psychological distress was measured with the NCCN Distress Thermometer (DT); quality of life was assessed with the EORTC QLQ-C30 at baseline and at 1, 3, 6, and 12 months post-surgery. Linear mixed-effects models were used, under both intention-to-treat (ITT) and per-protocol analyses, to test time-by-group interactions. Results Time-by-group interactions favored the intervention group for physical (ITT: F = 5.632, P < 0.001; PP: F = 6.084, P < 0.001), role (ITT: F = 3.325, P = 0.010; PP: F = 2.675, P = 0.031) and emotional functioning (ITT: F = 5.543, P < 0.001; PP: F = 5.566, P < 0.001), and for the distress thermometer (ITT: F = 3.791, P = 0.005; PP: F = 5.258, P < 0.001). Social functioning improved in the ITT analysis only ( P = 0.016); fati...