Preferences for HIV pre‐exposure prophylaxis among men who have sex with men and trans women in 15 countries and territories in Asia and Australia: a discrete choice experiment

作者：Warittha Tieosapjaroen, Benjamin R. Bavinton, Heather-Marie Ann Schmidt, Curtis Chan, Kim E. Green, Nittaya Phanuphak, Midnight Poonkasetwattana, Nicky S. Suwandi, Douglas Fraser, Hua Boonyapisomparn, Michael M. Cassell, Lei Zhang, Weiming Tang, Jason J. Ong · 发表于：Journal of the International AIDS Society · 年份：2025 · DOI：10.1002/jia2.70025 · 被引用次数：10 · 研究领域：HIV/AIDS Research and Interventions、HIV/AIDS drug development and treatment、Pneumocystis jirovecii pneumonia detection and treatment

INTRODUCTION: Scaling up pre-exposure prophylaxis (PrEP) for HIV among men who have sex with men (MSM) and transgender women (TGW) in the Asia-Pacific region has been slow. We identified the drivers of PrEP use and forecasted PrEP uptake given different PrEP programmes for MSM and TGW living in 15 countries and territories in Asia and Australia. METHODS: Separate online discrete choice experiment surveys for MSM and TGW were distributed in 15 Asian countries and territories and Australia between May and November 2022. We used random parameters logit models to estimate the relative importance of service attributes and predicted PrEP uptake for different programme configurations. RESULTS: Among 21,943 participants included in the MSM survey and 1522 in the TGW survey, the mean age was 31.7 (±9.5) years and 28.1 (±7.0) years, respectively. Cost emerged as the primary driver of PrEP use for MSM and TGW across countries, followed by the type of PrEP. When switching from the least preferred PrEP programme (i.e. very high service fee, PrEP implant, rare kidney problems as side effects of PrEP and a 2-monthly clinic visit) to an optimal programme (i.e. free access to PrEP via peer-led community clinics which offered sexually transmitted infection [STI] testing, and a 6-12 monthly visit), the predicted PrEP uptake could improve by over 50% for MSM in Australia, China, Hong Kong SAR China, Japan, the Philippines, Taiwan (China) and Thailand, and 37% for TGW. Compared to those at lower ...