Prevalence and relation to training of electrocardiographic findings in Caucasian children and adolescents 8- to 18-year-old practicing competitive sport

作者：Francesca Graziano, Amedeo De Antoni, Dorottya Balla, Laura Manfrin, Edoardo Oscar Genta, Laura Brusamolin, Franco Giada, Marco Scorcu, Nóra Sydó, Luigi Gerbino, Silvia Compagno, Béla Merkely, Hajnalka Vágó, Domenico Corrado, Alessandro Zorzi · 发表于：EP Europace · 年份：2025 · DOI：10.1093/europace/euaf180 · 被引用次数：4 · 研究领域：Cardiovascular Effects of Exercise、Cardiac electrophysiology and arrhythmias、Cardiac Arrhythmias and Treatments

AIMS: Training frequently induces electrocardiographic (ECG) changes that mimic heart diseases, requiring specific criteria for interpretation. Paediatric athletes represent a unique population as training-induced changes and those due to sexual maturation interact, and specific criteria may be needed. We aimed to assess the prevalence and its relation to training of ECG abnormalities in young athletes aged 8-18 years. METHODS AND RESULTS: We included 2458 young apparently healthy Caucasian athletes undergoing pre-participation screening. Electrocardiographic abnormalities were classified according to the 2017 International criteria (IC) by adding fragmented QRS and low QRS voltages in limb leads. A subgroup analysis was conducted to test the differences according to a 12-year-old age cut-off, the threshold for IC application. Common (>5%) findings included only mild sinus bradycardia (55-60 b.p.m.), early repolarization, incomplete right bundle branch block, voltage criteria for either left or right ventricular hypertrophy and T-wave inversion in V1-V3 before the age of 12. A heart rate of 50-55 b.p.m., first-degree atrioventricular block, right-axis deviation, and T-wave inversion in V1-V3 in athletes 12- to 16-year-old were uncommon (1-5%) and their prevalence was modulated by age, gender, and/or training status. All other ECG findings were rare (<1%). Ten (0.4%) athletes received an at-risk cardiovascular disease diagnosis including 6 with rare and 1 with uncommon ECG abn...