Unlocking microbiota potential: the role of organic copper in enhancing healthy white shrimp (Penaeus vannamei) farming

作者：Jinzhu Yang, Xiaoyang Yao, Zhong-Hao Zhang, Gang Lin, Mingzhu Li, Kangsen Mai, Yanjiao Zhang · 发表于：Animal Microbiome · 年份：2025 · DOI：10.1186/s42523-025-00450-8 · 被引用次数：3 · 研究领域：Invertebrate Immune Response Mechanisms、Aquaculture disease management and microbiota、Aquaculture Nutrition and Growth

BACKGROUND: Microbiota sequencing has emerged a powerful tool for advancing aquatic nutrition research. However, few studies have comprehensively investigated the host microbiota's response to trace minerals. This study examined the role of organic copper supplementation in promoting the health of farmed white shrimp (Penaeus vannamei) from a microbiota perspective. RESULTS: O) or organic copper (Cu-proteinate). The apparent digestibility coefficients of copper and zinc, along with carbon and nitrogen assimilation, were determined. The V3-V4 region of the 16S rRNA gene was sequenced from feeds, intestines, gills, and water samples. Shrimp that fed the organic copper diet demonstrated healthier physiological status, higher apparent digestibility coefficients of both copper and zinc, as well as greater accumulation of copper, zinc, carbon, and nitrogen. The organic copper group exhibited distinct microbial diversity and a more complex microbial co-occurrence network, characterized by enhanced natural connectivity and robustness. Keystone taxa, including Vibrio, Candidatus_Bacilloplasma, and Photobacterium, contributed to network stability. Taxa associated with nutrient metabolism, including Butyricicoccus, Lactobacillus, and genera in the family Lachnospiraceae, Prevotellaceae, Rikenellaceae and Ruminococcaceae, were significantly enriched, correlating well with improved nutritional profiles. In accordance, functional annotation revealed that the organic copper group exhibited ...