An investigation into the impact of family integrated care on extrauterine growth restriction at discharge in very low birth weight infants: a multi-centre study

作者：Mengfan Qiu, Yi Zhang, Yingzi Tang, Ya-Lan Dou, Yuan Wang, Tianchan Lyu, Qiaoling Fan, Yuelan Ma, Fang Li, Hui Rong, Yun-Fei Tang, Weiwei Gu, Xiaochun Chen, Dan Liu, Hua Wang, Juan Xiao, Lili Zhang, Yan Wang, Ruming Ye, Dan Li, Xiao-Xia Li, Yu Pang, Mei Lin, Mei Lin, Xuan Yan, Xiaojing Hu · 发表于：Journal of Global Health · 年份：2025 · DOI：10.7189/jogh.15.04168 · 被引用次数：2 · 研究领域：Infant Development and Preterm Care、Breastfeeding Practices and Influences、Infant Nutrition and Health

Background: Family integrated care (FIC) encourages parental involvement in neonatal intensive care units (NICU) and has been found to promote weight gain in preterm infants. Extrauterine growth restriction (EUGR) results from inadequate growth among very low birth weight infants (VLBWI), which has been found to contribute to parental anxiety. To address an existing gap in research, we aimed to examine the impact of parental involvement on EUGR at discharge in VLBWI. Methods: We conducted a retrospective, multi-centre case-control study involving VLBWIs admitted to 17 NICUs across eight southeastern Chinese provinces and cities from February 2021 to November 2023. We categorised cases and control groups based on the presence of EUGR at discharge and compared their perinatal and hospitalisation characteristics, as well as FIC duration, using a generalised linear mixed model. Results: EUGR in VLBWI at discharge was associated with birth weight (odds ratio (OR) = 0.547; 95% confidence interval (CI) = 0.490, 0.610), gestational week (<28 weeks) (OR = 3.101; 95% CI = 1.909, 5.038), Apgar score at 1 minute ≤7 (OR = 1.525; 95% CI = 1.119, 2.079), being small for gestational age (OR = 3.269; 95% CI = 1.547, 6.908), maternal gestational hypertension (OR = 1.868; 95% CI = 1.270, 2.748), necrotising enterocolitis (OR = 2.254; 95% CI = 1.386, 3.667), and total FIC duration. Based on literature and clinical practice, we divided the total FIC duration into three groups. We found that the l...