Adagrasib versus docetaxel in KRASG12C-mutated non-small-cell lung cancer (KRYSTAL-12): a randomised, open-label, phase 3 trial

作者：Fabrice Barlési, Wenxiu Yao, M. Duruisseaux, Ludovic Doucet, Aitor Azkárate Martínez, Vanesa Gregorc, Óscar Juan, Shun Lu, Charlotte De Bondt, Filippo de Marinis, Helena Linardou, Young‐Chul Kim, Robert M. Jotte, Enriqueta Felip, Giuseppe Lo Russo, Martin Reck, Mary F. Michenzie, Wenjing Yang, Julie Nicole Meade, Beata Korytowsky, Tony Mok, Tony S K Mok, Christoph Ackermann, Carlos Aguado De La Rosa, Andres Aguilar Hernandez, Samreen Ahmed, Aurelia Alexandru, Sara Alves, Lorenzo Antonuzzo, Surein Arulananda, Aitor Azkárate Martinez, Shobhit Baijal, Sofia Baka, Fabrice Barlesi, Patricia Barre, Alessandra Bearz, Piet Berber, Federica Biello, Roberto Bordonaro, Joaquim Bosch Barrera, Daniel Brungs, Jean-Luc Canon, Federico Cappuzzo, Enric Carcereny Costa, Bernabe Caro, Raquel Casas Cornejo, Lijuan Chen, Ying Cheng, Rita Chiari, Christos Chouaid, Daniel Christoph, Tudor-Eliade Ciuleanu, Romain Corre, Alexis Cortot, Marcia Cruz-Correa, Sinead Cuffe, Kristof Cuppens, Shaker Dakhil, Charlotte De Bondt, Maria De Los Reyes, Filippo De Marinis, Didier Debieuvre, Lore Decoster, Ingel Demedts, Manuel Dómine Gomez, Isabel Domingues, Xiaorong Dong, Ludovic Doucet, Michaël Duruisseaux, Ekkehard Eigendorff, Maria Encarnação Lionel Falchero, Yun Fan, Jian Fang, Enriqueta Felip, Gonzalo Fernández Hinojal, Antonio Manuel Ferreira Araujo, Sara Póvoa, Domenico Galetta, Maria Rosario Garcia Campelo, Carlo Genova, Paul Germonpré, Radj Gervais, Vanesa Gregorc, Laurent Greillier, Cesare Gridelli, Salvatore Grisanti, Wei Gu, Qisen Guo, Vanesa Gutiérrez Calderón, Lizza Hendriks, Jie Hu, Yanping Hu, Yi Hu, Maria Dolores Isla Casado, Bo Jin, Robert Jotte, Oscar Juan-Vidal, Coureche Kaderbhai, Christos Karapetis, Elisabeth A Kastelijn, Fergal Kelleher, Hye Ryun Kim, Mi-Hyun Kim, Young-Chul Kim, Konrad Kokowski, David König, Theodore Kontakiotis, Greg Korpanty, Athanasios Kotsakis, Dariusz Kowalski, Juraj Kultan, Jonas Kuon, George Lau, Patrick Lau, Hyun Woo Lee, Kye Young Lee, Jun Hyeok Lim, Helena Linardou, Colin Lindsay, Laiyu Liu, Giuseppe Lo Russo, Marta Lopez-Brea Piqueras, Shun Lu, Svetlana Lyubimova, Jeannick Madelaine, Slawomir Mandziuk, Omkar Marathe, Nicolas Martin, Celine Mascaux, Bartomeu Massuti Sureda, Dimitrios Mavroudis, Soledad Medina Valdivieso, Manilo Mencoboni, Giulio Metro, Janelle Meyer, Liyun Miao, Janusz Milanowski, Vincenzo Minotti, Fedor Moiseenko, Tony Mok, Tony Mok, Alessandro Morabito, Ioannis Mountzios, Andrzej Mruk, Veronika Müller, Tünde Nagy, Jarushka Naidoo, Sebahat Ocak, Sergey Orlov, Gyula Ostoros, Zulfiquer Otty, Rami Owera, Cheol-Kyu Park, Keon Uk Park, Nick Pavlakis, Eric Pichon, Maria Pilar Garrido Lopez, Miklos Pless, Araceli Priego, Mariano Provencio Pulla, Gilles Quéré, Harsha Ranganath, Jo Raskin, Markus Rauter, Niels Reinmuth, Gilles Robinet, Delvys Rodríguez Abreu, Gianpiero Romano, Jose Santos Barata, Michael Schenker, Roland Schott, Wolfgang Schütte, Telma Sequeira, Jianhua Shi, Merrill Shum, Denis Moro Sibilot, Seung Soo Yoo, Hector Soto Parra, Konstantinos Syrigos, Aleksandra Szczesna, Paola Taveggia, Macedo Teixeira, Marcello Tiseo, Pascale Tomasini, Gaurav Trikha, Javier Valdivia Bautista, Michel Van Den Heuvel, Kornelius Van Der Leest, Alain Vergnenegre, Nuria Viñolas, Jialei Wang, Jing Wang, Qian Wang, Yongsheng Wang, Thomas Wehler, Lin Wu, Wenxiu Yao, Feng Ye, Kejing Ying, Yan Yu, Silvia Zai, Jun Zhang, Wei Zhang, Jun Zhao, Jianying Zhou, Xiangdong Zhou, Wu Zhuang · 发表于：The Lancet · 年份：2025 · DOI：10.1016/s0140-6736(25)00866-9 · 被引用次数：50 · 研究领域：Lung Cancer Treatments and Mutations、Lung Cancer Research Studies、Cancer Immunotherapy and Biomarkers