An Analysis of Incidence, Related Factors and Prophylactic Treatments of Hospital-Acquired Upper Extremity Deep Vein Thrombosis: A Single-Center 13-Year Retrospective Study

作者：Wang Xiao, Yezu Liu, Jing Wang, Chun Bai, Xiaoming Zhang, Xuemin Zhang, Qingle Li, Wěi Li, Jingjun Jiang, Yang Jiao, Tao Zhang · 发表于：Clinical and Applied Thrombosis/Hemostasis · 年份：2025 · DOI：10.1177/10760296251365626 · 被引用次数：2 · 研究领域：Venous Thromboembolism Diagnosis and Management、Diagnosis and Treatment of Venous Diseases、Central Venous Catheters and Hemodialysis

Objectives This study aimed to evaluate the incidence trend and related factors for hospital-acquired upper extremity deep vein thrombosis (HA-UEDVT) in inpatients of a large medical center in China over 13 years, and to summarize and analyze the complications and preventive treatments of HA-UEDVT. Methods We conducted a retrospective analysis on the epidemiological characteristics, related factors, and use of different prophylactic anticoagulation methods in patients with HA-UEDVT at Peking University People's Hospital from January 1, 2009, to December 31, 2021. The data of all patients were obtained through the hospital's medical record system. Results Over the 13 years, there has been 239 cases of HA-UEDVT, with a much lower incidence rate compared to HA-LEDVT (0.31 vs 2.28 per 1000 admissions). HA-UEDVT incidence peaked in 2015 and 2016 (both 0.44 per 1000 admissions). The highest HA-UEDVT incidence rates were in the respiratory and gastroenterology departments, with 1.13 and 1.22 per 1000 admissions, respectively. The top three related factors of HA-UEDVT were having a CVC, concurrent of breast cancer, and concurrent of HA-LEDVT, with the β values of 4.81, 4.68, and 3.11, respectively. Thrombosis-related preventive measures were implemented in 30.1% of patients, significantly less frequently than HA-LEDVT (30.1% vs 82.4%, p < .001). The low molecular weight heparin (LMWH) subcutaneous injection being the main thromboprophylaxis used before HA-UEDVT diagnosis. Conclusi...