A narrative review of the ileal pouch in pediatric inflammatory bowel disease and familial adenomatous polyposis

作者：Anitta Philip, Allyson Wyatt, J. Rubén Rodriguez, Brad Pasternak, Lisa McMahon, Kalyani R. Patel, Richárd Kellermayer · 发表于：Journal of Pediatric Gastroenterology and Nutrition · 年份：2025 · DOI：10.1002/jpn3.70175 · 被引用次数：2 · 研究领域：Inflammatory Bowel Disease、Genetic factors in colorectal cancer、Microscopic Colitis

Ileal pouch-anal anastomosis is a surgical intervention in patients with medically refractory inflammatory bowel disease and familial adenomatous polyposis syndrome. Reported outcomes in children have been limited by both the retrospective nature and sample size of the investigations. In addition, there is a lack of consensus on surveillance guidelines in this patient population. Delay or lack of surveillance may increase the risk of complications (pouchitis, Crohn's disease-like inflammation, dysplasia, etc.). This narrative review aims to summarize the most recent literature (2013-2023) on short-term, long-term, and quality of life (QoL) outcomes in pediatric ileal pouch (J-pouch) patients. A proposed surveillance guidance is also provided.