Finger-to-Chest Style Transfer-Assisted Deep Learning Method for Photoplethysmogram Waveform Restoration With Timing Preservation

作者：Sara Maria Pagotto, Federico Tognoni, Matteo Rossi, Dario Bovio, Caterina Salito, Luca Mainardi, Pietro Cerveri · 发表于：IEEE Transactions on Instrumentation and Measurement · 年份：2025 · DOI：10.1109/tim.2025.3595240 · 被引用次数：6 · 研究领域：Non-Invasive Vital Sign Monitoring

Chest-acquired photoplethysmogram (PPG) signals often suffer from severe degradation due to motion artifacts and poor perfusion, limiting their clinical utility. We propose a novel style transfer–assisted cycle-consistent generative adversarial network (starGAN) to restore chest PPG signals using high-quality finger PPG as a reference during training. Leveraging a dual-sensor acquisition protocol, we avoid simulated artifacts and train the model to preserve physiological timing while improving wave-form quality across three PPG channels (red, green, infrared). Evaluation on over 8,000 5-second segments from 50 subjects showed a 30% improvement in waveform correlation and a 125% increase in signal-to-noise ratio over raw chest PPG. Pulse rate accuracy, compared to ECG, exceeded 84%. Multi-channel input significantly outperformed single-channel restoration, and starGAN achieved up to fourfold improvement over variational mode decomposition and other more advanced methods. Even under motion conditions (walking, stair climbing), the model improved signal quality by over 30%. These results highlight the effectiveness of cycle-consistent style transfer in restoring wearable PPG signals for reliable health monitoring from a single chest-worn sensor.